Articles of the week

Infertility affects 15% of couples, with male factor infertility influencing half of such couples [1]. Multiple environmental risk factors for male infertility have been identified, including: diet, exposure to pollution, and multiple substance abuses, e.g. alcohol, tobacco, marijuana, opiates [2]. In this issue of BJUI, the study of Antoniassi et al. [3] makes an important contribution to the literature regarding the impact of a particular environmental factor, smoking, on male factor infertility.…

Analysis of the functional aspects and seminal plasma proteomic profile of sperm from smokers Mariana Pereira Antoniassi*, Paula Intasqui*, Mariana Camargo*, Daniel Suslik Zylbersztejn*, Valdemir Melechco Carvalho†, Karina H. M. Cardozo† and Ricardo Pimenta Bertolla*‡ *Department of Surgery, Division of Urology, Human Reproduction Section, Sao Paulo Federal University, †Fleury Group, and ‡Hospital Sao Paulo, Sao Paulo, Brazil Objective To evaluate the effect…

Every Week the Editor-in-Chief selects an Article of the Week from the current issue of BJUI. The abstract is reproduced below and you can click on the button to read the full article, which is freely available to all readers for at least 30 days from the time of this post. In addition to the article itself, there is an accompanying editorial written by a prominent member of the urological community. This blog is intended to provoke comment and discussion and we invite you to use the comment…

An increasingly ageing and frail population undergoing cystectomy and urinary diversion has rekindled interest in urinary diversions with a lower risk of peri-operative complications, such as cutaneous ureterostomy (CU). The study in this issue of BJUI by Longo et al. [1] compares complications and quality of life in elderly patients with high comorbidities (American Society of Anesthesiologists [ASA] physical status score 3–4 and Charlson Comorbidity Index [CCI] ~5) receiving either…

Complications and quality of life in elderly patients with several comorbidities undergoing cutaneous ureterostomy with single stoma or ileal conduit after radical cystectomy Nicola Longo*, Ciro Imbimbo*, Ferdinando Fusco*, Vincenzo Ficarra†, Francesco Mangiapia*, Giuseppe Di Lorenzo‡, Massimiliano Creta§, Vittorio Imperatore§ and Vincenzo Mirone* *Department of Neurosciences, Sciences of Reproduction and Odontostomatology, University Federico II of Naples, Naples, †Urology Department,…

Every Week the Editor-in-Chief selects an Article of the Week from the current issue of BJUI. The abstract is reproduced below and you can click on the button to read the full article, which is freely available to all readers for at least 30 days from the time of this post. In addition to the article itself, there is an accompanying editorial written by a prominent member of the urological community. This blog is intended to provoke comment and discussion and we invite you to use the comment…

There have been numerous advances in the management of prostate cancer. Developments in imaging, surgical and radiotherapy technology, and pathological grading, have led to improvements in the diagnosis and management of this common malignancy. Such progress has translated to earlier diagnosis and improved disease-specific outcomes. With improved outcomes comes increased attention on life after treatment. Survivorship in cancer has been an area of increasing focus. The aim; to live as…

Every Week the Editor-in-Chief selects an Article of the Week from the current issue of BJUI. The abstract is reproduced below and you can click on the button to read the full article, which is freely available to all readers for at least 30 days from the time of this post. In addition to the article itself, there is an accompanying editorial written by a prominent member of the urological community. This blog is intended to provoke comment and discussion and we invite you to use the comment…

For the first time, Storebjerg et al. [1] describe the prevalence of the HOXB13 G84E mutation in a Danish population and its association with prostate cancer risk and features indicative of clinically aggressive disease in a cohort of men undergoing radical prostatectomy. In this study, the prostate cancer risk mutation was seen in 0.49% of controls with an ~5-fold increase in risk of prostate cancer among carriers. The homeobox transcription factor gene HOXB13, is located on the long arm of chromosome…