Objectives To perform a systematic review and meta‐analysis aiming to improve the level of evidence and determine the efficacy and safety of low‐intensity shockwave therapy (LiST) in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods We searched PubMed, Cochrane Library and Scopus databases from inception to November 2020 for randomised controlled trials (RCTs) exploring […]
Abstract Objective To assess the activity and safety of sequential 177Lu‐PSMA‐617 and docetaxel versus docetaxel on a background of androgen deprivation therapy (ADT) in men with de novo metastatic hormone‐naïve prostate cancer (mHNPC). 177Lu‐PSMA‐617 is a novel targeted radioligand therapy directed against prostate specific membrane antigen (PSMA). We hypothesise that 177Lu‐PSMA‐617 will be effective and […]
Abstract Introduction The novel optical techniques such as blue light cystoscopy (BLC) during transurethral resection of bladder tumor (TURBT) has been shown to improve the tumor detection rate and recurrence rate. Whether a single immediate intravesical chemotherapy (SIIC) still has an additive therapeutic effect in the setting of these novel optical techniques (e.g., photodynamic diagnosis […]
Abstract Objective To determine whether repeated FDG‐PET‐CT‐scans can predict increased disease‐specific survival after induction chemotherapy followed by radical cystectomy. Patients & Methods Between 2007 and 2018, 86 patients with clinically node‐positive bladder cancer (T1‐T4, N1‐N3, M0‐M1a) were included and underwent a repeated FDG‐PET‐CT during cisplatin‐based induction chemotherapy. The 71 patients that displayed response to chemotherapy […]
Abstract Priapism is a medically neglected disorder for which traditional treatment is primarily aimed at resolving its acute phase. Patients with priapism recurrences, termed recurrent ischemic priapism (RIP), are commonly subjected to frequent ER visits and invasive procedures without significant improvement in the course of their condition. Many eventually undergo radical, circumventive treatments including androgen […]
Objective To describe the natural history, reconstructive solutions, and functional outcomes of those men undergoing pubectomy and urinary reconstruction after prostate cancer treatment. Patients and Methods This study retrospectively identified 25 patients with a diagnosis of urosymphyseal fistula (UF) following prostate cancer therapy who were treated with urinary reconstruction with pubectomy. This study describes the […]
Abstract Objectives To report long‐term follow‐up outcomes after masculinising surgery in disorders/differences of sex development (DSD), including both physicians and the patient’s perspectives on appearance and functional outcome, including sexuality. Patients and methods In total, 1040 adolescents (≥16 years) and adults with a DSD took part in this multicentre cross‐sectional clinical study in six European […]
Abstract Objectives To report long‐term follow‐up outcomes after masculinising surgery in disorders/differences of sex development (DSD), including both physicians and the patient’s perspectives on appearance and functional outcome, including sexuality. Patients and methods In total, 1040 adolescents (≥16 years) and adults with a DSD took part in this multicentre cross‐sectional clinical study in six European […]
Abstract Objectives To evaluate the diagnostic performance of fluorescent voided urine cytology (FVUC) using a novel automated detection technology to screen for primary bladder cancer and for surveillance of recurrent bladder tumor. Patients and Methods We created a rapid, objective, automated, and high‐throughput detection device for hexylaminolevulinate‐mediated FVUC, named the cellular fluorescence analysis unit‐II (CFAU‐II)”. […]
Abstract Objectives To evaluate the diagnostic performance of fluorescent voided urine cytology (FVUC) using a novel automated detection technology to screen for primary bladder cancer and for surveillance of recurrent bladder tumor. Patients and Methods We created a rapid, objective, automated, and high‐throughput detection device for hexylaminolevulinate‐mediated FVUC, named the cellular fluorescence analysis unit‐II (CFAU‐II)”. […]