Author Archive for: Jonathan Epstein

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Entries by Jonathan Epstein

Editorial: The prognostic value of prostate biopsy grade – Forever a product of sampling

January 25, 2017/1 Comment/by Jonathan Epstein

The ability to project clinical outcomes based on limited data is crucial to the practice of medicine. This principle is particularly germane to the management of prostate cancer, where clinical outcomes vary widely. In the current issue of BJUI, Danneman et al. [1] assess pathological grade concordance between diagnostic needle biopsy and subsequent radical prostatectomy specimens […]

Editorial: Current Gleason score 3 + 4 = 7: has it lost its significance compared with its historical counterpart?

June 1, 2016/by Jonathan Epstein

Berg et al. [1] report that patients classified as Gleason score 7 (3 + 4) according to the revised grading system published in 2005 are to some extent similar to patients with pre-2005 Gleason score 6, at least in terms of risk of biochemical recurrence. The logical but not necessarily correct conclusion is that current patients with Gleason […]