Author Archive for: admin Z.9

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Entries by admin Z.9

July 2018 – About the Cover

This issue’s Article of the Month is a multicentre trial led by researchers in Cambridge, UK. The cover shows a typical Cambridge scene of bicycles leaning against a college wall. Cambridge is home to the world-renowned University of Cambridge, which was founded in 1209. The city’s skyline is dominated by several college buildings, along with the spire […]

Editorial: β3‐adrenoceptor agonists inhibit calcium oscillations in bladder detrusor

The β3‐adrenoceptor (β3‐AR) agonist mirabegron has now been used clinically for the treatment for overactive bladder (OAB) for 5 years, but it is still not clear either exactly where the β3‐ARs are located within the bladder wall or entirely how they work. β3‐AR agonists can reduce detrusor contractions after cholinergic stimulation, but the concentrations of mirabegron […]

Video: β3‐adrenoceptor agonists inhibit carbachol‐evoked Ca2+ oscillations in murine detrusor myocytes

 β3‐adrenoceptor agonists inhibit carbachol‐evoked Ca2+ oscillations in murine detrusor myocytes   Abstract Objective To test if carbachol (CCh)‐evoked Ca2+ oscillations in freshly isolated murine detrusor myocytes are affected by β3‐adrenoceptor (β‐AR) modulators. Materials and Methods Isometric tension recordings were made from strips of murine detrusor, and intracellular Ca2+ measurements were made from isolated detrusor myocytes using […]

June 2018 – About the Cover

In the month that brings the BAUS annual meeting to Liverpool, the Article of the Month is a BAUS consensus document and so the cover features the sign for the Beatles Story museum in Liverpool. The Museum contains recreations of The Casbah Coffee Club, The Cavern Club and Abbey Road Studios among other historical Beatles items, such as John Lennon‘s spectacles, George […]

Article of the Week: Comparing LRP and RARP to ORP to treat PCa

Every Week, the Editor-in-Chief selects an Article of the Week from the current issue of BJUI. The abstract is reproduced below and you can click on the button to read the full article, which is freely available to all readers for at least 30 days from the time of this post. In addition to the article […]

Editorial: RARP and a Parachute

Radical prostatectomy is probably the most scrutinized, debated and re‐invented procedure in the field of urology. This is with good reason. Dr Hugh Hampton Young gave the first formal account of a radical treatment for prostate cancer in 1905. It was a procedure performed perineally with the prime intention of total cancer extirpation. The oncological […]

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